FeaturedProduct updates · 10 September 2026
Independent Verification and BRAKES-Strata
We have made some significant updates to the BRAKES platform, with two major releases of functionality, BRAKES-Strata and regulatory testing.
Read the postAll news & insights
News
Tom Coates on AI For Pharma Growth: why interim analysis is due an upgrade
Our CEO, Tom Coates, joined Dr Andree Bates on AI For Pharma Growth to talk about interim analysis, why so few trials use it well, and what it would take to catch futility and success years sooner.
3 September 2026
Insights
Optimal Stoppage of Doomed Processes
Most clinical trials fail, and a failing trial keeps enrolling patients who cannot benefit while costing money. Yet a substantial share of commercial trials run no interim look at all, and those that do typically check only once, near the halfway point, stopping if the treatment appears futile.
4 August 2026
News
Presentient in Clinical Leader: when one trial leads to rethinking them all
Clinical Leader's chief editor, Dan Schell, has published a piece on our co-founder Dan Nicolau and the observation that led to Presentient.
22 July 2026
Insights
FIFA World Cup Rule Change Proposal - Leading By 5 Goals Leads to an Automatic Win
Leading by 5 goals is significant. So significant in fact that in the entire 163 year old history of the modern game a 5 goal lead has never been overturned in a top flight game. Maybe time for a rule change?
15 July 2026
News
Presentient has received comments from FDA providing clarity on how sponsors can use BRAKES
The FDA comments clarify how the FDA anticipates BRAKES being deployed; sponsors seeking to use BRAKES in the context of a specific clinical trial are to engage with the FDA via individual IND submissions.
2 July 2026
Insights
Presentient Proposes Pilot in Response to FDAs AI-Enabled Optimization of Early-Phase Clinical Trials Pilot Program RFI
The FDA comments clarify how the FDA anticipate BRAKES being deployed; sponsors seeking to use BRAKES in the context of a specific clinical trial are to engage with the FDA via individual IND submissions.
30 June 2026
Insights
Whitepaper: BRAKES helps trials stop years earlier
The BRAKES platform accelerates decision-making by months to years while eliminating operational bias.
19 January 2026
Insights
The FDA says yes to Bayes
The FDA's momentous shift on the use of Bayesian methods
9 January 2026
9 posts
Press inquiries: press@presentient.comUpdates
Get updates by email
New posts, product updates and company news, sent directly to your inbox.
Unsubscribe at any time. See our privacy notice.
Go deeper
into the science.
See the statistical foundation behind Pre.sentient and how continuous analysis works in practice.